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I was just thinking about my story Leigh Anne. What if I could somehow make her chromosomes very, very unusual? Like maybe, YXXX, or XXYX, or even XXXY? I need to do a little research to see if maybe that is even plausible. It would explain Leigh Anne's circumstances.
Hugs,
Barbara
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Comments
All of those are the same thing
XXXY is the way it is represented. The Xs come before the Ys. XXY and XXXY are considered variations of Klinefelter's Syndrome, which you can easily research with der Google. :)
Hugs,
Erin
= Give everyone the benefit of the doubt because certainty is a fragile thing that can be shattered by one overlooked fact.
Keep adding letters, and
Keep adding letters, and it'll look like knitting or cross-stitch!
I'll get a life when it's proven and substantiated to be better than what I'm currently experiencing.
Klinefelter's Syndrome
I have a friend locally with this. Not fun, but she's post-op and living a good life with her wife.
Googled this
This might help you. Seems very in-depth.
http://www.encyclopedia.com/topic/Klinefelter_syndrome.aspx
Hugs,
Erica
Don't think so.
We know of cases with one extra chromosome (Klinefelter's syndrome{xxy},XXX ,Down syndrom and XYY ) and all of them cause some sort of development issues (And XYY is the lesser of the whole bunch by a long mile ) , extra genes means more problem so extra chromosomes will lead to a lot more problem .The person has a larger chance for having more genes creating "faulty" proteins or what would have been normal proteins under normal circumstances but are causing issues due to the increase quantities of them.That's twice as true when it comes to the sex chromosome , as they contain all sorts of problematic genes in the first place (Anderson-Fabry for example ).
So while XXYY and XXXX do exist ( I don't think 48,XXXY was ever found ) they are rare and can cause all sorts of issues.
Hope that helps.
Lily.
Genetics
In general, extra copies of any gene are A Bad Thing. We normally have two copies of each gene (with one obvious exception for slightly under half the population!), and each gene typically has two forms (alleles in genetics jargon) - a dominant form (i.e. you only need one copy of that form for the gene to be 'expressed'), and a recessive form (i.e. you need two copies - one from each parent - for the form to be 'expressed').
Genetic disorders tend to be 'recessive', so if you've got an extra copy of a chromosome (each of which has several hundred genes), you have a much higher chance of several recessive traits being expressed. The obvious example is Down's Syndrome, which occurs with three copies of Chromosome 21.
It stands to reason that the more copies of either of the sex chromosomes you have, the more problems you're likely to have. Klinefelter's Syndrome covers XXY and XXXY, while 49, XXXXY Syndrome covers four Xs. There's also XXYY Syndrome, XYY Syndrome, Triple X Syndrome (get your mind out of the gutter!), 48, XXXX and even 49, XXXXX. That should give you a general flavour, as well as a rough guide to the likely results of other combinations.
As the right side of the brain controls the left side of the body, then only left-handers are in their right mind!