Gender Tinkering In Utero

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I'm speechless. I'll let this, and the linked articles, speak for themselves:

http://slog.thestranger.com/slog/archives/2010/06/29/doctor-...

Comments

Day Million

erin's picture

Look up the story "Day Million" by Frederik Pohl. It's about a predicted gender-non-compliant male fetus manipulated in utero to be born female. Exactly what a lot of people here would want?

Things like this are going to happen and ethical decisions will have to be made.

Hugs,
Erin

= Give everyone the benefit of the doubt because certainty is a fragile thing that can be shattered by one overlooked fact.

= Give everyone the benefit of the doubt because certainty is a fragile thing that can be shattered by one overlooked fact.

Or the Star Trek Episode...

Puddintane's picture

The Outcast, in which a heterosexual pairing between Riker and a woman named Soren is seen as a perverted aberration which is cured through forced reparative "psychotectic" therapy. At the end of the episode Soren is shown as being glad that she was cured of the heterosexual disease.

Cheers,

Puddin'

-

Cheers,

Puddin'

A tender heart is an asset to an editor: it helps us be ruthless in a tactful way.
--- The Chicago Manual of Style

I don't understand

Frank's picture

How do they even get approval to try this drug on pregnant women? Do the women who are being given this shit understand all the ramifications?? Scary scary stuff...like there really is "normal" GRRRRRrrrrrrrrrrrrr

{{Hugs}}

Hugs

Frank

Dear Frank -- Is That "Anne" Frank?

Without an accepted "normal" there could be no bigotry, which would severely handicap all those with pent-up hate that needs an outlet. Everyone serves a purpose in life. Some of us fill the void for those who like dogs too much to kick them.

Angela Rasch (Jill M I)

Angela Rasch (Jill M I)

Does anyone remember DES?

It was a drug to prevent miscarrages that was taken in the 30's to 70's era. There are many complaints that the use of the drug caused Cancer, and all sorts of other problems including Transgenderisim. You can bet that if the drug is ever proven to cause all these things, we will never hear about it.

K

Aside from being whacky pseudoscience...

Puddintane's picture

since homosexuality of any kind isn't associated with "disease," there are listed uses of the drug for many purposes, including obstetrical problems.

Dexamethasone can be used in the context of congenital adrenal hyperplasia, to prevent virilisation of a female fetus. If one or both parents are carriers of mutations to the CYP21 (CYP21A2) gene, the mother may start dexamethasone treatment within 7 weeks of conception. At the 12th week, a chorionic villus sample will determine whether the fetus is male (in which case the dexamethasone is stopped) or female. Subsequent DNA analysis can then reveal whether the female fetus is a carrier of the mutation, in which case dexamethasone treatment must continue until birth. The side-effects for the mother can be severe and the long-term impact on the child is not clear.

Note that CAH is a very serious disease which may prove fatal to the foetus, but the jump from endocrine virilisation to lesbianism is pure quackery. Some of the most "virile" women I know are raging heterosexuals, and quite a few lesbians make Tyra Banks look butch.

Dexamethasone may be given to women at risk of delivering prematurely in order to promote maturation of the fetus' lungs. This has been associated with low birth weight, although not with increased rates of neonatal death.

Interestingly, Dexamethasone is also given to mountain climbers as a treatment for altitude sickness, and to prostitutes to improve their appearance (but not their actual health) after experiencing the effects of debilitating disease and drug addiction.

As a prophylactic measure to guard against lesbianism, it's probably about as effective as paint the nursery pink and signing the girl up for ballet lessons. Oh! Wait! There are a lot of lesbian ballet dancers... Possibly a diagnostic test to identify abusive jerks in utero might be more effective, if combined with an embedded microchip so one could simply wave a discreet detection scanner at them before agreeing to a first date.

Perhaps they could even install scanners at the entrances to saloons and public houses -- as a public service -- so that an alarm horn would sound and red lights start flashing when a putz walked through the door.

Eventually, the trait might even be bred out of the human race, given sufficient time.

Cheers,

Puddin'

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Cheers,

Puddin'

A tender heart is an asset to an editor: it helps us be ruthless in a tactful way.
--- The Chicago Manual of Style

Curiously

Andrea Lena's picture

my mother-in-law was prescribed DES for obstetrical purposes in the late 40's, even though there was no anticipation of any problem. She had nine children, two of whom are twins, along with at least one miscarriage. RE: low birth weights, my wife's younger brother was small enough at birth to fit into a Christmas stocking. My wife was born two months premature, and was small enough at birth to fit into the palm of the doctor's hand. Resultant from the early birth she is blind in one eye. In addition, there was enough remaining tissue to indicate that she had a twin who had not developed.

Here's a thought. Maybe the procedure described above could be used to eliminate prejudice and hatred. Oh wait, those aren't characteristics; they're choices. Oh well.

She was born for all the wrong reasons but grew up for all the right ones.
Con grande amore e di affetto, Andrea Lena

  

To be alive is to be vulnerable. Madeleine L'Engle
Love, Andrea Lena

Gays and Lesbians in Evolution

I read a study where the Author surmised that geing gay or lesbian was merely an effort of the evolutionary process to find ways around environmental barriers. It is self limiting anyhow, since two people of the same sex can not have children and I really see no need to stupidly moralize about it. It is hard for me to find a place in the evolutionary chain for transgendered folk except to say that something just did not work out according to our very limited knowlege of the scheme of things.

K

self limiting?

Puddintane's picture

Hardly. Having relatives who are interested in one is good for survival. One might as well say that grandparents are worthless because they can't make babies any more, so the human race would be better off if everyone died at fifty.

Maiden aunts, bachelor brothers, and the whole panoply of familial relationships are the real keys to human survival. We are defined as humans -- and humane -- by our generosity and compassion, not by our lapses into selfishness and cruelty. Altruism survives in many species -- not just us -- because it's an adaptive behaviour, and some of the most successful and long-lasting species in the long history of the world have been the most altruistic. Ants labour not for themselves, but for the offspring of their sisters, yet ants, the vast majority of whom never have babies of their own, are ubiquitous in the world.

Cheers,

Puddin'

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Cheers,

Puddin'

A tender heart is an asset to an editor: it helps us be ruthless in a tactful way.
--- The Chicago Manual of Style

And More!

Besides oral and injected uses of dex, it's available in preparations for ophthalmic and dermatologic uses, as ointments and drops.

I'm pretty sure I've had it injected in my foot, squirted in my eyes and spread on my skin, over the years, for this and that minor problem.

For the record, CAH is a non-trivial disorder, which affects lots more than prenatal genital development. It comes in several types and severities, most of the fetal cases which I understand to be fatal, either causing miscarriage or early infant death due to unmanageable salt-wasting. It's the minority of "mild" fetal cases that let babies survive with "only" improperly developed genitals. I believe there's also an adolescent-onset variety with, again, very serious implications.

Whether it's desirable to try to nurse a sick fetus along and suppress the damage of a genetic defect until birth (a birth that will often carry serious lifetime medical needs and a short life), or better to recommend the parents abort and try again is a bioethics question probably more worth addressing than the one at hand, and subject to the context of parental genetics, fertility, age, religion, etc. But, this deranged doctor thinking that this kind of prenatal medical treatment is justified solely for the goal of lowering the already minor probability of lesbianism... sheesh!

This sounds scarily like cloning and robotics

Given humanity's abysmal record on most other subjects, what makes 'the powers that be' certain that they know better? Not that it's stopped them before.

Nature delights in diversity; why can't humanity?

Susie