There's an interesting TED video given by Martine Rothblatt which talks partly about her transition at Ted talks click here.

However, there's a whole lot more about how she moved from being a satellite communication engineer to form a medical company to keep alive her daughter who has a life-threatening illness, and about digitally saving our minds so we can be reborn at some time in the future!

For those that don't know of them, TED stands for Technology, Entertainment and Design, and the website contains videos of well-presented lectures on all kind of fascinating subjects.