TG Mainstream Comic Book Characters

While surfing around on the net I cam across a 1950's Strange Tales of Suspense for sale in which the seller claimed it was the ONLY occurrence of mainstream transgenderism in comics.

[Not so. There are dozens!], I immediately thought to myself, and two names were at the top of the list as major characters, even. So I looked up some biography links for them and sent them along to the seller as a friendly gesture. Then I thought, [Well! I'll bet the folks over at BCTS would be interested in info like this!], and so I provide it here:

1. Courier
   • Jake / Jacqueline Gavin
     • a mutant in the Marvel Universe
       • [Mutant High's Page for Courier]
2. Shvaughn Erin
   • Sean / Shvaughn Erin
     • a Science Police Officer and the Liason for the SP to the Legion of Super Heroes in the DC Universe
       • [Spider Bob's DC Heroes Page for Shvaughn Erin]

And there are others. And not just MtFs... For example, the new Spider-Woman (who happens to be J. Jonah Jameson's niece!) masqueraded as Spider-Man when Parker had given it up (yes, again) until he felt guilty about someone else risking themself in his stead and picked up his webs. Then he confronted "him" and found that it was a young girl in a padded suit.